Hypersensitive Response Elicited by Erwinia amylovora Harpin Requires Active Plant Metabolism . Sheng Yang He. Department of Plant Pathology, Cornell University, Ithaca, NY 14853 U.S.A. David W. Bauer, Alan Collmer, and Steven V. Beer. Department of Plant Pathology, Cornell University, Ithaca, NY 14853 U.S.A. MPMI 7:289-292. Accepted 10 December 1993. This article is in the public domain and copyrightable. It may be freely reprinted with customary crediting of the source. The American Phytopathological Society, 1994.

Biochemical processes involved in hypersensitive plant cell death were explored with purified harpin and inhibitors of eukaryotic metabolic processes, (-Amonitin, cycloheximide, vanadate, lanthanum, and WIN50805 prevented or delayed the HR elicited by harpin in tobacco leaves; k-252a and staurosporine had no effect. In contrast, the K+/H+ exchange response of tobacco cell cultures elicited by harpin was inhibited by only lanthanum and k-252a