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Genomics of Phytopathogenic Fungi and the Development of Bioinformatic Resources

May 2002 , Volume 15 , Number  5
Pages  421 - 427

Darren M. Soanes , 1 Wendy Skinner , 2 John Keon , 2 John Hargreaves , 2 and Nicholas J. Talbot 1

1School of Biological Sciences, University of Exeter, Washington Singer Laboratories, Perry Road, Exeter, EX4 4QG, U.K.; 2Institute of Arable Crops Research, Long Ashton Research Station, Long Ashton, Bristol, U.K.


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Accepted 18 January 2002.

Genomic resources available to researchers studying phytopathogenic fungi are limited. Here, we briefly review the genomic and bioinformatic resources available and the current status of fungal genomics. We also describe a relational database containing sequences of expressed sequence tags (ESTs) from three phytopathogenic fungi, Blumeria graminis, Magnaporthe grisea, and Mycosphaerella graminicola, and the methods and underlying principles required for its construction. The database contains significant annotation for each EST sequence and is accessible at http://cogeme.ex.ac.uk. An easy-to-use interface allows the user to identify gene sequences by using simple text queries or homology searches. New querying functions and large sequence sets from a variety of phytopathogenic species will be incorporated in due course.



© 2002 The American Phytopathological Society