Fusarium Head Blight (FHB), caused by Fusarium graminearum, is one of the most devastating diseases of wheat as it reduces both the yield and quality of the crop. Deploying genetic resistance is the most economical and sustainable strategy to manage FHB. However, only a few genes conferring partial quantitative resistance against FHB are known. The susceptibility genes pave a new way to the genetic control as compared to much commonly used resistance genes. The objective of this study is to map a susceptibility gene for FHB on chromosome 7A of wheat. Deletion lines and substitution lines for 7A along with Chinese Spring and Nulli7A as controls were used for the study. Genome specific markers were developed and each deletion line was molecularly characterized. Plants were screened in the greenhouse for their response to FHB by point inoculations with F. graminearum at pre-anthesis stage. The disease scoring was done at 14, 21, and 28 days after inoculation. Comparative analysis of the molecular and phenotypic data revealed the gene to be present in the pericentromeric region. Further work on reducing the genetic interval having the potential susceptibility gene is in progress and results will be presented.