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Comparative Interaction of n-dodecylguanidine Acetate With Four Plant Pathogenic Fungi. J. A. Bartz, Research Assistant, Department of Plant Pathology, University of Wisconsin, Madison 53706, Present address of senior author: Department of Plant Pathology, University of Florida, Gainesville 32601; J. E. Mitchell, Professor, Department of Plant Pathology, University of Wisconsin, Madison 53706. Phytopathology 60:345-349. Accepted for publication 19 September 1969. DOI: 10.1094/Phyto-60-345.

The relative tolerance of Venturia inaequalis, Blumeriella jaapii, Fusarium solani f. sp. phaseoli, and Colletotrichum orbiculare in continuous exposure (fungistatic test) to n-dodecylguanidine acetate (dodine) was in the ratio 1:4:14:30, respectively, determined as ed50 doses. The difference in reaction of F. solani and C. orbiculare was in part due to the time required for toxic dose to be sorbed. F. solani was more sensitive to short exposures than was C. orbiculare. The time course of sorption varied among the organisms. The amount taken up increased continually with B. jaapii and C. orbiculare, increased to a plateau with V. inaequalis, and increased to a peak followed by an apparent decrease in sorbed material with F. solani. The latter may involve a detoxification that would explain the relative tolerance of this organism to dodine.