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Figure 6. Experimental inoculation on the stem of a potted
Datura stramonium (Jimson weed) plant with A. tumefaciens
(electron micrograph). After 2-3 weeks, a crown gall tumor is generated.
The integration of the T-DNA originating from the Ti plasmid harbored
in A. tumefaciens is visualized by in situ T-DNA-DNA hybridization
of the crown gall chromosome within gall tissue. The T-DNA was labeled
with tritium and the integrated T-DNA hybridization is seen as a dark
band (white arrow) as detected by x-ray emulsion film layered on the chromosomes
from cells in crown gall. (Courtesy C. Kado) |