Tobacco Mosaic Virus:
One Hundred Years of Contributions to Virology

On Beijerinck’s Concept of a Contagium Vivum Fluidum

Milton Zaitlin

Anon. 1898. Prof. Beijerinck, on a contagium vivum fluidum, causing the spot-disease
     of tobacco leaves. Nature 59:216
Beijerinck, M. W. 1898. Concerning a contagium vivum fluidum as a cause of the spot
     disease of tobacco leaves. In: "Phytopathological Classics, No. 7" (J. Johnson, ed.).
     American Phytopathological Society, pp. 33-52

H. H. McKinney and Cross Protection

Robert W. Fulton

McKinney, H. H. 1929. Mosaic diseases in the Canary Islands, West Africa,
     and Gibraltar. Journal of Agricultural Research 39:557-578

Francis O. Holmes and the Local Lesion Assay

John G. Shaw

Holmes, F. O. 1929. Local lesions in tobacco mosaic. Botanical Gazette 87:39-55

The Chemical Nature of Tobacco Mosaic Virus Particles

Bryan D. Harrison

Stanley, W. M. 1935. Isolation of a crystalline protein possessing the properties of
     tobacco-mosaic virus. Science 81:644-645
Bawden, F. C., Pirie, N. W., Bernal, J. D., and Fankuchen, I. 1936. Liquid crystalline
     substances from virus-infected plants. Nature 138:1051-1052

Commentary on Bernal and Fankuchen

Gerald Stubbs

Bernal, J. D., and Fankuchen, I. 1937. Structure types of protein ‘crystals’ from virus-
     infected plants. Nature 139:923-924
Bernal, J. D., and Fankuchen, I. 1941. X-ray and crystallographic studies of plant virus
     preparations. III. Journal of General Physiology 25:147-165

The Electron Microscopy of Tobacco Mosaic Virus

Robert W. Horne

Kausche, G. A., Pfankuch, E., and Ruska, H. 1939. Die Sichtbarmachung von
     pflanzlichem Virus im Übermikroskop. Naturwissenschaften 27:292-299

Commentary on the Two Papers by Caspar and Franklin

Aaron Klug

Caspar, D. L. D. 1956. Radial density distribution in the tobacco mosaic virus particle.
     Nature 177:928
Franklin, R. E. 1956. Location of the ribonucleic acid in the tobacco mosaic virus
     particle. Nature 177:928-930

UV Irradiation of Tobacco Mosaic Virus

Albert Siegel

Siegel, A., and Wildman, S. G. 1956. The inactivation of the infectious centersof tobacco
     mosaic virus by ultraviolet light. Virology 2:69-82

In Vitro Assembly of Tobacco Mosaic Virus

George Lomonossoff

Fraenkel-Conrat, H., and Williams, R. C. 1955. Reconstitution of activetobacco mosaic
     virus from its inactive protein and nucleic acid components. Proceedings of the
     National Academy of Sciences (USA) 41:690-698

TMV in Tübingen (1945–1965)

K.W. Mundry

Gierer, A., and Schramm, G. 1956. Infectivity of ribonucleic acid from tobaccomosaic virus.
     Nature 177:702-703
Gierer, A., and Mundry, K.-W. 1958. Production of mutants of tobacco mosaic virusby
     chemical alteration of its ribonucleic acid in vitro. Nature 182:1457-1458
Wittmann, H. G. 1960. Comparison of the tryptic peptides of chemically induced and
     spontaneous mutants of tobacco mosaic virus. Virology 12:609-612

Comments on Takebe and Otsuki

Milton Zaitlin

Takebe, I., and Otsuki, Y. 1969. Infection of tobacco mesophyll protoplastsby tobacco
     mosaic virus. Proceedings of the National Academy of Sciences (USA) 64:843-848

Identification of the TMV Coat Protein Messenger RNA

Andrew O. Jackson

Hunter, T. R., Hunt, T., Knowland, J., and Zimmern, D. 1976. Messenger RNA for the coat 
     protein of tobacco mosaic virus. Nature 260:759-764

The Tale of the Two-Tailed Monsters

Ken Richards

Lebeurier, G., Nicolaieff, A., and Richards, K. E. 1977. Inside-out modelfor self-assembly
     of tobacco mosaic virus. Proceedings of the National Academyof Sciences (USA)
     74:149-153
Butler, P. J. G., Finch, J. T., and Zimmern, D. 1977. Configuration of tobacco mosaic virus 
     RNA during virus assembly. Nature 265:217-219

Transport of Tobacco Mosaic Virus From Cell-to-Cell

Masamichi Nishiguchi and Fusao Motoyoshi

Nishiguchi, M., Motoyoshi, F., and Oshima, N. 1978. Behaviour of a temperature
     sensitive strain of tobacco mosaic virus in tomato leaves and protoplasts.
     Journal of General Virology 39:53-61

Cotranslational Disassembly of Tobacco Mosaic Virus

T. Michael A. Wilson

Wilson, T. M. A. 1984. Cotranslational disassembly of tobacco mosaic virus in vitro.   
     Virology 137:255-265

Avoiding the Triple Flip and Two Twists in Cloning TMV

William O. Dawson

Goelet, P., Lomonossoff, G. P., Butler, P. J., Akam, M. E., Gait, M. J., and Karn, J. 1982. 
     Nucleotide sequence of tobacco mosaic virus RNA. Proceedings of the National
     Academy of Sciences (USA) 79:5818-5822
Dawson, W. O., Beck, D. L., Knorr, D. A., and Grantham, G. L. 1986. cDNA cloning of
     the complete genome of tobacco mosaic virus and production of infectious transcripts.
     Proceedings of the National Academy of Sciences (USA) 83:1831-1836

Coat Protein Mediated Resistance

Roger N. Beachy

Abel, P. P., Nelson, R. S., De, B., Hoffmann, N., Rogers, S. G., Fraley, R. T., and Beachy, 
     R. N. 1986. Delay of disease development in transgenic plants that express the
     tobacco mosaic virus coat protein gene. Science 232:738-743

The 54 kDa Protein Encoded by Tobacco Mosaic Virus and Replicase-Mediated Resistance

Milton Zaitlin

Golemboski, D. B., Lomonossoff, G. P., and Zaitlin, M. 1990. Plants transformed with a
     tobacco mosaic virus nonstructural gene sequence are resistant to the virus.
     Proceedings of the National Academy of Sciences (USA) 87:6311-6315